Description
- Omega-3 essential polyunsaturated fatty acids have distinct chemical structures and physiologic functions that distinguish them from other families of essential fatty acids.
- Often lacking in Western diets, omega-3 fatty acids compete with other fatty acids in the body for cyclooxygenase (COX) and lipoxygenase (LOX) enzyme metabolism, incorporation into cell membranes, and the synthesis of lipid mediators.1-3
- The long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are almost exclusively marine-derived and act together to influence membrane fluidity and signal transduction pathways.4
- EPA and DHA are abundantly enriched in the retina, brain, and heart tissues.5-7 Each have preferential distribution within the phospholipid bilayer of cell membranes and have been shown to exert unique biological actions.
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